Two people were found dead at the Southern California mansion of "When Harry Met Sally" director and actor Rob Reiner on Sunday, local broadcaster NBCLA and other media outlets reported.
The Los Angeles Fire Department told NBC a man and a woman, approximately 78 and 68 years old, were found deceased inside.
The authorities later confirmed that the bodies were of the American film director and his wife, producer Michelle Reiner, Forbes reported citing Variety and other published reports.
Robbery-homicide division detectives have been assigned to the case.
Neighbours said that property records that indicate Reiner and his wife lived in the home in the upscale Brentwood neighborhood, NBC reported.
Rob and Michelle had been married since May 1989. Rob Reiner was previously married to actor-director Penny Marshall from 1971 to 1981.
Reiner rose to acting fame as the oafish son-in-law Michael "Meathead" Stivic on groundbreaking 1970s sitcom "All in the Family," before transitioning to directing with rock mockumentary "This is Spinal Tap" in 1984.
Reiner directed the 1989 romantic comedy "When Harry Met Sally," starring Billy Crystal and Meg Ryan.
Reiner’s most recent film was "Spinal Tap II: The End Continues", the sequel to the 1984 classic "This Is Spinal Tap".
He collected Emmys as best supporting actor in a comedy in 1974 and 1978.
He has writing credits in "The Smothers Brothers Comedy Hour", "Happy Days" and "All in the Family" and a pair of TV movies under his belt.
Reiner moved into big screen work as a director, writer and co-star in 1984’s "This is Spinal Tap", the cherished mockumentary about a thick-headed heavy metal band.
That project was succeeded during the next decade by a run of box office hits and popular favorites, including "Stand By Me" (1986), a coming-of-age drama adapted from a Stephen King short story; the fantasy "The Princess Bride" (1987); the new-look romantic comedy "When Harry Met Sally" (1989); another King adaptation, the thriller "Misery" (1990); and the Tom Cruise-Jack Nicholson court martial drama "A Few Good Men" (1992).
Rob Reiner and his wife are survived by children, Jake, Nick and Romy.